un·screw / ˌənˈskroō/ • v. (with reference to a lid or other object held in place by a spiral thread) unfasten or be unfastened by twisting: [tr.] Will unscrewed the cap from a metal flask | [intr.] the spout usually unscrews or lifts off easily. ∎ [tr.] detach, open, or slacken (something) by removing or loosening the screws holding it in place.