All Sources -
Updated Media sources (1) About encyclopedia.com content Print Topic
HLA system (human leucocyte antigen system) A series of four gene loci (A, B, C, and D) in humans that code for a group of glycoproteins, present on the surface of plasma membranes, that act as antigens and are important in determining the acceptance or rejection by the body of a tissue or organ transplant (see graft). These antigens are one group of the so-called histocompatibility proteins (see histocompatibility). Two individuals with identical HLA types are said to be histocompatible. Successful transplantation requires a minimum number of HLA differences between the donor's and recipient's tissues. See also major histocompatibility complex.
HLA system n. human leucocyte antigen system: a series of four gene families (termed A, B, C, and D) that code for polymorphic proteins expressed on the surface of most nucleated cells. Individuals inherit from each parent one gene (or set of genes) for each subdivision of the HLA system. If two individuals have identical HLA types, they are said to be histocompatible. Successful tissue transplantation requires a minimum number of HLA differences between donor and recipient tissues.
More From encyclopedia.com
Adipose Tissue , adipose tissue Body fat–the cells that synthesize and store fat, releasing it for metabolism in fasting. Also known as white adipose tissue, to disti… Gene , The gene is the physical unit of heredity. For each physical trait—such as eye color, height, hair color—a person inherits two genes or two groups of… Alkaptonuria , Definition Alkaptonuria is a rare, inherited disorder characterized by urine that turns dark when exposed to air, dark pigmentation of the cartilage… Medical Transplantation , Modern medicine continues to offer many miracles that lengthen the life spans of humans, as well as greatly increase the quality of life that they en… , neuron • , exon •Agamemnon, Memnon •ninon, xenon •noumenon • Trianon • xoanon •organon • Simenon • Maintenon •crampon, kampong, tampon •Nippon • coupon •Akron,… Regulator Gene , regulatory gene In the operon theory of gene regulation, a gene that is involved in switching on or off the transcription of structural genes. When t…
You Might Also Like