pre·des·tine / prēˈdestin/ • v. [tr.] (usu. be predestined) (of God) destine (someone) for a particular fate or purpose: Calvinists believed that every person was predestined by God to go to heaven or to hell. ∎ determine (an outcome or course of events) in advance by divine will or fate: she was certain that fate was with her and everything was predestined | [as adj.] (predestined) our predestined end.