Secobarbital, prescribed and sold as Seconal, is a short-acting Barbiturate used principally as a Sedative-Hypnotic drug but occasionally as a preanesthetic agent. It is a nonspecific central nervous system (CNS) depressant and greatly impairs the mental and/or physical abilities necessary for the safe operation of automobiles and complex machinery.
Before the introduction of the Benzodiazepines, it was the drug most commonly used to treat insomnia. Prolonged or inappropriate use of secobarbital can produce Tolerance and Physical Dependence. If high doses have been used, abrupt cessation can result in severe Withdrawal symptoms that include convulsions. Secobarbital is more likely to be abused than benzodiazepines and appears to produce greater euphoria in certain individuals than would a comparable sedative dose of a benzodiazepine. Consequently, it is classified as a Schedule II class drug in the Controlled Substances Act, which indicates that although it is acceptable for clinical use, it is considered to have a high abuse potential. As with other barbiturates, it should never be combined with another CNS depressant because respiratory depression can occur.
(See also: Abuse Liability of Drugs: Testing in Humans ; Drug Interaction and the Brain ; Drug Interactions and Alcohol )
Hobbs, W. R., Rall, T. W., & Verdoorn, T. A. (1996) Hypnotics and sedatives; ethanol. In J. G. Hardman et al. (Eds.), The pharmacological basis of therapeutics, 9th ed. (361-396). New York: McGraw-Hill.
Scott E. Lukas
"Secobarbital." Encyclopedia of Drugs, Alcohol, and Addictive Behavior. . Encyclopedia.com. (October 21, 2018). http://www.encyclopedia.com/education/encyclopedias-almanacs-transcripts-and-maps/secobarbital
"Secobarbital." Encyclopedia of Drugs, Alcohol, and Addictive Behavior. . Retrieved October 21, 2018 from Encyclopedia.com: http://www.encyclopedia.com/education/encyclopedias-almanacs-transcripts-and-maps/secobarbital
Encyclopedia.com gives you the ability to cite reference entries and articles according to common styles from the Modern Language Association (MLA), The Chicago Manual of Style, and the American Psychological Association (APA).
Within the “Cite this article” tool, pick a style to see how all available information looks when formatted according to that style. Then, copy and paste the text into your bibliography or works cited list.
Because each style has its own formatting nuances that evolve over time and not all information is available for every reference entry or article, Encyclopedia.com cannot guarantee each citation it generates. Therefore, it’s best to use Encyclopedia.com citations as a starting point before checking the style against your school or publication’s requirements and the most-recent information available at these sites:
Modern Language Association
The Chicago Manual of Style
American Psychological Association
- Most online reference entries and articles do not have page numbers. Therefore, that information is unavailable for most Encyclopedia.com content. However, the date of retrieval is often important. Refer to each style’s convention regarding the best way to format page numbers and retrieval dates.
- In addition to the MLA, Chicago, and APA styles, your school, university, publication, or institution may have its own requirements for citations. Therefore, be sure to refer to those guidelines when editing your bibliography or works cited list.