Mon·gol·oid / ˈmänggəˌloid/ • adj. 1. sometimes offens. of or relating to the broad division of humankind including the indigenous peoples of eastern Asia, Southeast Asia, and the Arctic region of North America.2. (mongoloid) often offens. affected with Down syndrome.• n. 1. sometimes offens. a person of a Mongoloid physical type.2. offens. a person with Down syndrome.