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Bladder Augmentation

Bladder Augmentation

Definition
Purpose
Description
Diagnosis/Preparation
Aftercare
Risks
Normal results
Morbidity and mortality rates
Alternatives

Definition

Bladder augmentation, also known as augmentation cystoplasty, is reconstructive surgery to increase the reservoir capacity of the bladder. The procedure is very common and involves tissue grafts (anastomosis) from a section of the small intestine (bowel), stomach, or other substitutes that are attached to the urinary bladder by sewing or stapling. Whether due to chronic obstructive bladder damage, birth defects that resulted in small reservoir capacity, or dysfunction due to nerve innervation of the bladder muscle (sphincter), surgery is chosen only after a thorough medical work-up that involves assessment of the lower urinary tract, functional physiological evaluation, and anatomic assessment. Some laparoscopic methods (surgery with a fiber-optic instrument inserted through the abdomen) of bladder augmentation have been tried, but reports indicate that these are technically arduous and may not have the long-lasting effects of open surgery.

Purpose

Bladder dysfunction and incontinence may be due to problems with the reservoir capacity of the bladder or with the “gatekeeping” muscle (the sphincter), which, instructed by the brain, allows urine to build up or to be released. Bladder augmentation is used to treat serious and irreversible forms of incontinence and to protect the upper urinary tract (kidney function) from reflexia (urine back up to the kidneys). Many candidates for the surgery are highly compromised individuals with other serious conditions like spinal cord injuries and multiple sclerosis, as well as patients likely to undergo kidney transplantation. Patients who undergo bladder augmentation must be free of bowel and urethral disease and be able to perform self-catheterization (place a urinary tube into their urethra).

Description

Standard augmentation involves segments of the bowel used to create a pouch or wider wall for the bladder in order to enhance its reservoir capacity. Often this reconstruction surgery is accompanied by procedures that tighten the neck of the bladder as well. Until the 1970s it was thought that those with bladder dysfunction could be treated with bladder diversion, and that this procedure offered a simple and safe means of emptying the bladder. However, it was soon discovered that pressure from the bladder caused irreparable damage to the kidneys, with 50% of patients exhibiting such deterioration. The new diagnostic assessment of the bladder as well as the need for a new medical intervention for patients with severe bladder dysfunction opened the way for urinary tract reconstruction. Today, many techniques are available, along with new types of grafting substitutions.

The basic procedure involves open abdominal surgery with removal of a 10–12-in (25–30-cm) segment of ileum (part of the large intestine), or the ileocecum (the junction of small and large intestines) cut down the middle (detubularized), and shaped into a U-configuration with a pouch at the bottom. This opening or pouch will be the “patch” for the bladder. During surgery, the bladder itself is also opened at the dome and cut at right angles to create a clam-like shape. The open bowel “patch” is then attached to the bladder with sutures or stapling.

Diagnosis/Preparation

Patients selected for bladder augmentation are chosen after they undergo a thorough physical exam, x-ray tests, and bladder physiology tests, as well as a renal and bladder ultrasound for any dilation of the kidneys or ureters or kidney obstruction. A VCUG (holding and voiding urine) test is performed to assess the contour of the bladder and to assess for ureteral reflux (back up of urine to the kidneys). Finally, a cystometrogram (CMG) is performed in the physician’s office to judge the pressure and volume levels

at which the urine leakage occurs. Once the tests, patient history, and physical exam are completed, a treatment plans commence.

The patient should plan for up to two weeks in the hospital. The patient will have been on a low-residue diet for a few days before admission. Surgery will take

KEY TERMS

Anastomosis— The surgical union of parts and especially hollow tubular parts.

Catherization— the use of or insertion of a catheter (as in or into the bladder, trachea, or heart).

Cystoplasty— Reconstructive surgery of the urinary bladder.

Neurogenic bladder— A urinary problem of neurological origin in which there is abnormal emptying of the bladder with subsequent retention or incontinence of urine.

Ureter— Either of the paired channels that carry urine from a kidney to the bladder.

place two to three days after hospital admittance. In the hospital, a general examination will be performed and blood taken. The bowel will need to be cleaned in preparation. Clear fluids will be given, as well as a strong laxative prior to surgery.

Aftercare

Early complications of surgery include cardiovascular, thromboembolic (blood clot), gastrointestinal, and respiratory complications associated with major abdominal surgery. Many patients require three months after surgery to allow their augmented bladder to establish itself. This involves a special diet for a few months. The patient also should be aware that the augmented bladder empties after their own (native) bladder. Two weeks after surgery, tests are performed to ensure that the patch is leak proof. Once a watertight reservoir is demonstrated, the catheters and drains that were introduced for surgery are removed.

Risks

Long term risks of the procedure include peptic ulceration of the bladder and perforation of the gastric segment. Spontaneous perforation is rare but it is life threatening and has a 25% mortality rate. Other risks include bacterial infections, metabolic changes, urinary tract infections, and urinary tract stones. Nocturnal incontinence is sometimes a problem after the surgery.

Normal results

Although some patients recover spontaneous voiding function, this does not occur with reliable predictability. Preoperatively, patients should be prepared for

WHO PERFORMS THE PROCEDURE AND WHERE IS IT PERFORMED?

Bladder augmentation is performed by a urological surgeon, who is an MD with advanced training in urology. He or she should have had special surgical training for this type of surgery. The surgery takes place in a general hospital.

the likelihood that they will have to perform lifelong intermittent catherization and irrigation of the augmented bladder. Other effects are a special diet for up to three months and pain after surgery.

Morbidity and mortality rates

Reported surgical risks include 3-5.7% rate of adhesive small bowel obstruction requiring operative intervention; 5-6% incidence of wound infection; and up to 3% reoperation rate for bleeding. Long term complications include a 50% unchanged bladder compliance and renal deterioration. No reduction in growth in children has been reported, but the procedure is not recommended for children who have not reached puberty unless there is the threat of kidney damage without surgery.

Alternatives

Bladder augmentation is a medical treatment of last resort for those patients unable to avoid incontinence through medical alternatives. Other surgeries may be indicated if the individual is not a candidate for self-catherization or has other medical or psychological conditions that would rule out bladder augmentation.

Resources

BOOKS

Dewan, P., and M. E. Mitchell, eds. Bladder Augmentation. Oxford Press, 2000.

PERIODICALS

Abrams, P., S. K. Lowry, et al. “Assessment and Treatment of Urinary Incontinence.” Lancet 355 (June 2000): 2153–58

Fantl, J. A., D. K. Newman, J. Colling, et al. “Urinary Incontinence in Adults: Acute and Chronic Management. Clinical Practice Guideline, Number 2, 1996.” Agency for Health Policy and Research Publications (March 1996).

QUESTIONS TO ASK THE DOCTOR

  • How many bladder augmentation surgeries do you perform a year?
  • What complications of this surgery do you think are the most likely and/or worrisome?
  • Are there other patients with my underlying medical conditions who have had this surgery that I could contact?
  • Is there a pre-operative patient group with this hospital that could help me understand my rehabilitation and help with the compliance with the diet and self-catherization?

Greenwell, T. J., S. N. Venn, and A. R. Mundy. “Augmentation Cystoplasty.” British Journal of Urology International 88, no. 6 (October 2001): 511–534.

Qucek, M. I., and D. A. Ginsberg. “Long-term Urodynamics Follow-up of Bladder Augmentation for Neurogenic Bladder.” Urology 169 (January 2003): 195–198.

Rackley, R. R., and J. B. Abdelmalak. “Radical Prostatectomy: Laparoscopic Augmentation Cystoplasty.” Urological Clinics of America 28 (August 2001).

ORGANIZATIONS

National Association for Continence. P.O. Box 8310 Spartanburg, SC 29305. (800) BLADDER, (252-3337). http://www.nafc.org.

National Kidney and Urologic Diseases Information Clearinghouse. 3 Information Way, Bethesda, MD 20892-3580. (301) 654-4415. http://www.niddk.nih.gov.

The Simon Foundation for Continence. P.O. Box 835 Wilmette, IL 60091. (800) 23SIMON (237-4666). http://www.simonfoundation.org.

OTHER

“Bladder Augmentation.” Dr. Rajhttp. [cited April 2003]. http://www.drrajmd.com/treatments/treatments.htm.

Carr, Michael, and M. E. Mitchell. “Bladder Augmentation.” Digital Urological Journal [cited April 2003]. http://www.duj.com/Article/Carr/Carr.html.

“Neurogenic Bladder.” [cited April 2003]. http://www.med.wayne.edu/urology/DISEASES/neurogenicbladder.html.

Nancy McKenzie, Ph.D.

Bladder removal seeCystectomy

Bladder resection seeTransurethral bladder resection

Bladder tumor antigen test seeTumor marker tests

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