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Factor VIII

Factor VIII (antihaemophilic factor) One of the blood clotting factors. Factor VIII is a soluble protein that stimulates the activation of Factor X by Factor IXa, which in turn converts prothrombin to thrombin, thus causing the fibrin matrix of a blood clot to form. Haemophilia is due to a deficiency or defect of Factor VIII and is treated by administration of blood plasma or plasma concentrate containing the factor. Factor VIII can now be obtained from genetically engineered cell cultures. Such preparations avoid the risk of contamination with viruses, notably HIV (the AIDS virus).

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Factor VIII

Factor VIII (antihaemophilic factor, AHF) (fak-ter) n. a coagulation factor normally present in blood. Deficiency of the factor, which is inherited by males from their mothers, results in haemophilia A.

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"Factor VIII." A Dictionary of Nursing. . Encyclopedia.com. 21 Aug. 2018 <http://www.encyclopedia.com>.

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"Factor VIII." A Dictionary of Nursing. . Retrieved August 21, 2018 from Encyclopedia.com: http://www.encyclopedia.com/caregiving/dictionaries-thesauruses-pictures-and-press-releases/factor-viii

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