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re·sign / riˈzīn/ • v. 1. [intr.] voluntarily leave a job or other position: he resigned from the government in protest at the policy. ∎  [tr.] give up (an office, power, privilege, etc.): four deputies resigned their seats. ∎  [intr.] Chess end a game by conceding defeat without being checkmated: he lost his queen and resigned in 45 moves.2. (be resigned) accept that something undesirable cannot be avoided: he seems resigned to a shortened career she resigned herself to a lengthy session. ∎ archaic surrender oneself to another's guidance: he vows to resign himself to her direction.DERIVATIVES: re·sign·ed·ly / riˈzīnədlē/·sign·ed·ness / riˈzīnədnəs/·sign·er n.