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- Isaac ben Samuel of Dampierre
- Isaac ben Sheshet Perfet
- Isaac ben Solomon
- Isaac ben Todros
- Isaac ben Todros of Barcelona
- Isaac ben Yakar
- Isaac Benjamin Wolf ben Eliezer Lipman
- Isaac from Ourville
- Isaac Nappa?a
- Isaac of Chernigov
- Isaac of Evreux
- Isaac of Monte Luco, St.
- Isaac of Southwark
- Isaac of Stella
- Isaac the Blind
- Isaac the Good of Langres, St.
- Isaac the Great, Armenian Catholicos, St.
- Isaac, Jules Marx
- Isaac, Testament of
- Isaacs