haemolysis The breakdown of red blood cells. A normal occurrence, chiefly in the blood sinuses of the spleen, when the cells are ageing after 3–4 months in circulation, but it can happen abnormally in the circulating blood, causing haemolytic anaemia. In either case, the cells become more fragile than normal, disintegrate, and shed their contents. Normally the haemoglobin is broken down and recycled, so its iron is not lost. When free haemoglobin is released in the plasma, some products are retained, but excessive amounts are excreted from the kidneys (haemoglobinuria). Fragility of cells in a blood sample can be assessed by placing them in a series of salt solutions of progressively lower osmolality than the blood itself, which causes them to swell, and finding the osmolality at which they burst.
See blood; haemoglobin.
See blood; haemoglobin.
haemolysis (hi-mol-i-sis) n. the destruction of red blood cells (erythrocytes). Within the body, haemolysis may result from poisoning, infection, or the action of antibodies; it may occur in mismatched blood transfusions. It usually leads to anaemia. See also laking.
haemolysis The breakdown of red blood cells. It may be due to the action of disease-causing microorganisms, poisons, antibodies in mismatched blood transfusions, or certain allergic reactions. It produces anaemia.
More From encyclopedia.com
Blood , blood, fluid pumped by the heart that circulates throughout the body via the arteries, veins, and capillaries (see circulatory system; heart). An adu… Erythrocyte , e·ryth·ro·cyte / iˈri[unvoicedth]rəˌsīt/ • n. a red blood cell that (in humans) is typically a biconcave disc without a nucleus. Erythrocytes contain… Hemoglobin , As a component of blood , hemoglobin can be an important facet of a forensic investigation, especially to help detect the illegal practice known as "… reticulocyte , reticulocyte Immature precursor of the red blood cell in which the remains of the nucleus are visible as a reticulum. Very few are seen in normal blo… Hematocrit , Definition The hematocrit is a test that measures the volume of blood by the percentage that is comprised of red blood cells. The hematocrit is also… Blood Count , Definition One of the most commonly ordered clinical laboratory tests, a blood count, also called a complete blood count (CBC), is a basic evaluation…
About this article
All Sources -
Updated Aug 24 2016 About encyclopedia.com content Print Topic
You Might Also Like