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fist / fist/ • n. a person's hand when the fingers are bent in toward the palm and held there tightly, typically in order to strike a blow or grasp something.• v. 1. [tr.] hit with or as with the fists or a fist: a fastball he fisted into left field.2. (also fist-fuck) [tr.] vulgar slang penetrate (a person's anus or vagina) with one's fist.PHRASES: make a —— fist of (or at) inf. do something to the specified degree of success: I think he's made a good fist of it.DERIVATIVES: fist·ed adj. [in comb.] bare-fisted.fist·ful / -ˌfoŏl/ n.