A neurological examination is an essential component of a comprehensive physical examination. It is a systematic examination that surveys the functioning of nerves delivering sensory information to the brain and caring motor commands (Peripheral nervous system) and impulses back to the brain for processing and coordinating (Central nervous system).
A careful neurological evaluation can help to determine the cause of impairment since a clinician can begin localizing the problem. Symptoms that occur unexpectedly suggest a blood vessel or seizure problem. Those that are not so sudden suggest a possible tumor. Symptoms that have a waning course with recurrences and worsen over time suggest a disease that destroys nerve cells. Others that are chronic and progressive indicate a degenerative disorder. In cases of trauma, symptoms may be evident upon inspection and causes maybe explained bythird party witnesses. Some patients may require extensive neurological screening examination (NSE) and/or neurological examination (NE) to determine the cause. The NH will assist the clinician to diagnose illnesses such as seizure disorders, narcolepsy, migraine disorders, dizziness , and dementia.
A neurological screening is an essential component of every comprehensive physical examination. In cases of neurological trauma, disease, or psychological disorders patients are usually given a very in-depth neurological examination. The examination is best performed in a systematic manner, which means that there is a recommended order for procedures.
Neurological screening examination
The NSE is basic procedure especially in patients who have a general neurological complaint or symptoms. The NSE consists of six areas of assessment:
- mental status: assessing normal orientation to time, place, space, and speech
- cranial nerves: checking the eyes with a special light source (ophthalmoscope), and also assessment of facial muscles strength and functioning
- motor: checking for tone, drift, heal, and toe and walking
- sensory: cold and vibration tests
- coordination: observing the patient walk and finger to nose testing
- reflexes: using a special instrument the clinician taps an area above a nerve to emit a reflex (usually movement of muscle groups)
The NE should be performed on a patient suspected of having neurological trauma, neurological, or psychological diseases. The NE is performed in a systematic and comprehensive manner. The NE consists of several comprehensive and in-depth assessments of mental status, cranial nerves, motor examination, reflexes, sensory examination, and posture and walking (gait) analysis.
MENTAL STATUS EXAMINATION (MSE) There are two types of MSE, informal and formal. The informal MSE is usually done when clinicians are obtaining historical information from a patient. The formal MSE is performed in a patient suspected of a neurological problem. The patient is commonly asked his/her name, the location, the day, and date. Retentive memory capability and immediate recall can be assessed by determining the number of digits that can be repeated in sequence. Recent memory is typically examined by testing recall potential of a series of objects after defined times, usually within five and 15 minutes. Remote memory can be assessed by asking the patient to review in a coherent and chronological fashion, his or her illness or personal life events that the patient feels comfortable talking about. Patient recall of common historical or current events can be utilized to assess general knowledge. Higher functioning (referring to brain processing capabilities) can be assessed by spontaneous speech, repetition, reading, naming, writing, and comprehension. The patient may be asked to perform further tasks such as identification of fingers, whistling, saluting, brushing teeth motions, combing hair, drawing, and tracing figures. These procedures will assess the intactness of what is called dominant (left-sided brain) functioning or higher cortical function referring to the portion of the brain that regulates these activities.
The MSE is particularly important in the specialty of psychotherapy. Psychotherapists recommend an in-depth MSE to all patients with possible organic (referring to the body) or psychotic disorders. This examination is also performed in a systematic and orderly manner. It is divided into several categories:
- Appearance: This assessment determines the patient's presentation, i.e., how the patient looks (clothes posture, grooming, and alertness).
- Behavior: This assesses the patient's motor (movements) activity such as walking, gestures, muscular twitching, and impulse control.
- Speech: The patient's speech can be examined concerning volume, rate of speech and coherence. Patients who exhibit latent or delayed speech can indicate depression, while a rapid or pressured speech may suggest possible mania or anxiety.
- Mood and affect: Normal mood is term euthymia. There is variation in mood presentations and patients may display a flat, labile, blunted, constructed or inappropriate mood. The patient can also be euphoric (elevated) or dysphoric (on the down side).
- Thought processes and content: This category is typically assessed by determining word usage (can indicate brain disease), thought stream (whether thoughts are slow, restricted, blocked, or overabundant), continuity of thought (referring to associations among ideas), and content of thought (delusional thoughts).
- Perception: This assessment examines the patient's ability to hear, see, touch, taste, and smell. Certain psychological states may cause hearing and visual hallucinations. Impairments of smell and touch are usually caused by medical (organic) causes or as side effects from certain medications.
- Attention and concentration: This clinician assesses the patient's ability to focus on a specific task or activity. Abnormalities in attention and concentration can indicate problems related to anxiety or hallucinations.
- Orientation: The patient is examined for orientation to time, place, and identification of self (asking the patient his/her name). Disturbances in orientation can be due to a medical condition (other than psychological), substance abuse, or as a side effect of certain medications such as those used to treat depression, anxiety or psychosis (since these medications usually have a sedative affect).
- Memory: Patients are examined for remote, recent, and immediate memory capabilities. Remote and recent memory can be assessed by the patient's ability to recall historical and current events. Immediate memory can be tested by naming three objects and asking the patient to repeat the named objects immediately, then after five and 15 minute intervals.
- Judgment: This category evaluates the patient's ability to exercise appropriate judgment. It also determines whether the patient has an understanding of consequences associated with their actions.
- Intelligence and information: The only precise measurement for this category can be obtained by administering specialized intelligence tests, However a preliminary assessment of intelligence can be made based on the patient's fund of information, general knowledge, awareness of current events, and the ability for abstract thinking (thinking of unique concepts).
- Insight: Insight in the MSE pertains to the patient's awareness of their problem that prompted them to seek professional examination. Insight concerning the present illness can range from denial to fleeting admission of current illness.
CRANIAL NERVES (CN) Cranial nerves are specialized nerves that originate in the brain and connect to specialized structures such as the nose, eyes, muscles in the face, scalp, ear, and tongue.
- CNI: This nerve checks for visual capabilities. Patients are usually given the Snellen Chart (a chart with rows of large and small letters). Patients read letters with one eye at a time.
- CN III, IV, and VI: These nerves examine the pupillary (the circular center structure of the eye that light rays enter) reaction. The pupils get smaller, normally when exposed to the light. The eyelids are also examined for drooping or retraction. The eyeball is also checked for abnormalities in movement.
- CNV: The clinician can assess the muscles on both sides of the scalp muscles (the temporalis muscle). Additionally the jaw can be tested for motion resistance, opening, protrusion, and side-to-side mobility. The cornea located is a transparent tissue covering the eyeball and could be tested for intactness by lightly brushing a wisp of cotton directly on the outside of the eye.
- CNVII: Examination of CNVII assesses asymmetry of the face at rest and during spontaneous movements. The patient is asked to raise eyebrows, wrinkle forehead, close eyes, frown, smile, puff cheeks, purse lips, whistle, and contract chin muscles. Taste for the front and middle portions of the tongue can also be examined.
- CNVIII: Testing for this CN deals with hearing. The clinician usually uses a special instrument called a tuning fork and tests for air conduction and structural problems which can occur inside the ear.
- CN IX and X: These tests will evaluate certain structures in the mouth. The clinician will usually ask the patient to say “aah” and can detect abnormal positioning of certain structures such as the palateluvula. The examiner will also assess the sensation capabilities of the pharynx, by stimulating the area with a wooden tongue depressor, causing a gag reflex.
- CNXI: This nerve is usually examined by asking the patient to shrug shoulders (testing a muscle called the trapezius) and rotating the head to each side (testing a muscle called the sternocleidomastoid). These muscles are responsible for movement of the shoulders and neck. The test is usually done with resistance, meaning the examiner holds the area while the patient is asked to move. This is done to assess patient's strength in these areas.
- CNXII: This nerve tests the bulk and power of the tongue. The examiner looks for tongue protrusion and/or abnormal movements.
MOTOR EXAMINATION The motor examination assesses the patient's muscle strength, tone, and shape. Muscles could be abnormally larger than expected (hypertrophy) or small due to tissues destruction (atrophy). It is important to assess if there is evidence of twitching or abnormal movements. Involuntary movements due to tics or myoclonus can be observed. Additionally, movements can be abnormal during maintained posture in neurological disorders such as Parkinson's disease. Muscle tone is usually tested by applying resistance to passive motion of a relaxed limb. Power is assessed for movements at each joint. Decreases or increases in muscle tone can help the examiner localize the affected area.
REFLEXES The patient's reflexes are tested by using a special instrument that looks like a little hammer. The clinician will tap the rubber triangular shaped end in several different areas in the arms, knee, and Achilles heal area. The clinician will ask the patient to relax and gently tap the area. If there is a difference in response from the left to right knee, then there may be an underlying problem that merits further evaluation. A difference in reflexes between the arms and legs usually indicates of a lesion involving the spinal cord. Depressed reflexes in only one limb, while the other limb demonstrates a normal response usually indicates a peripheral nerve lesion.
SENSORY EXAMINATION Although a very essential component of the NE, the sensory examination is the least informative and least exacting since it requires patient concentration and cooperation. Five primary sensory categories are assessed: vibration (using a tuning fork), joint position (examiner moves the limb side-to-side and in a downward position), light touch, pinprick, and temperature. Patients who have sensory abnormalities may have a lesion above the thalamus. Spinal cord lesions or disease can possibly be detected by pinprick and temperature assessment.
COORDINATION The patient is asked to repetitively touch his nose using his index finger and then to touch the clinician's outstretched finger. Coordination can also be assessed by asking the patient to alternate tapping the palm then the back of one hand on the thigh. For coordination in the lower extremities on legs, the patient lies on his or her back and is asked to slide the heel of each foot from the knee down the shin of the opposite leg and to raise the leg and touch the examiners index finger with the great toe.
WALKING (GAIT) Normal walking is a complex process and requires usage of multiple systems such as power, coordination and sensation working together in a coordinated fashion. The examination of gait can detect a variety of disease states. Decreased arm swinging on one side is indicative of corticospinal tract disease. A stooped down posture and short-stepped gait may suggest Parkinson's syndrome. A high stepped, slapping gait may be the result of a peripheral nerve disease.
The MSE is the first step in a continuous assessment to determine the diagnosis a psychotherapist should take a detailed medical history in the process of ruling out a general medical condition. If a general medical disease is suspected, referral is indicated to rule out this category. Once a medical condition has been fully excluded the therapist can then localize the components of an abnormal MSE to determine the underlying psychological disorder. Once this is determined treatment may include, but is not limited to therapy sessions and/or medication. For neurological diseases the clinician will use information gained from the NE for ordering further tests. These tests may include a complete blood analysis, liver function tests, kidney function tests , hormone tests, and a lumbar puncture to determine abnormalities in cerebrospinal fluid. In cases of trauma (car accident, sports injury) the NE is a quick and essential component of emergency assessment. One a diagnosis is determined emergency measures may include further tests and/or surgery.
Corticospinal tract —A tract of nerve cells that carries motor commands from the brain to the spinal cord.
Gait —Referring to walking motions.
Reflex —A response, usually a movement, elicited by tapping on the nerve with a special hammer-like instrument.
Thalamus —A part of the brain that filters incoming sensory information.
Care is usually specific once the final diagnosis has been determined. In psychological cases the treatment may include therapy and/or medication. In causes of an acute insult such as stroke or trauma, the patient is usually admitted to the hospital for appropriate treatment. Some neurological diseases are chronic and require conservative (medical) treatment and frequent follow-up visits for monitoring and stability or progression of the disease state. The MSE and NE are good diagnostic tools. Further testing using advanced technological procedures is usually required for definitive diagnosis and initiation of disease-specific treatment.
The outcome depends ultimately on the final diagnosis. Neurological diseases typically follow a chronic course. Situations that present as trauma may require surgical intervention and intensive care with an outcome usually proportional to extent of injuries. Psychological disorders may require long term (chronic) treatment and/or medication(s). Most neurological conditions require follow-up and periodic monitoring.
Behrman, Richard E., et al, editors. Nelson Textbook of Pediatrics. 16th ed. W. B. Saunders Company, 2000.
Goldman, Lee, et al. Cecil's Textbook of Medicine. 21st ed. W. B. Saunders Company, 2000.
Laith Farid Gulli M.D.
Bilal Nasser M.Sc.