haemolytic disease of the newborn
haemolytic disease of the newborn n. the condition resulting from destruction (haemolysis) of the red blood cells of the fetus by antibodies in the mother's blood passing through the placenta. This most commonly happens when the red blood cells of the fetus are Rh positive (see rhesus factor) but the mother's red cells are Rh negative. The fetal cells are therefore incompatible in her circulation and evoke the production of antibodies. This may result in very severe anaemia of the fetus or severe jaundice after birth. A blood test early in pregnancy enables the detection of antibodies in the mother's blood and the adoption of various precautions for the infant's safety. See also anti D.
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haemolytic disease of the newborn
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haemolytic disease of the newborn