Manizales (mänēsä´lās), city (1993 pop. 303,136), alt. 7,063 ft (2,153 m), capital of Caldas dept., W central Colombia, on the slopes of the Cordillera Central. It is a commercial and agricultural center in a region that produces a large share of Colombia's coffee. There are minor industries in the city and some gold and silver mines nearby. Manizales was founded in 1847 by gold prospectors. The city was destroyed by an earthquake in 1878 and by fire in 1925. It is the seat of Caldas Univ.