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Lac operon

Lac operon The operon that controls the synthesis of acetylase, permease, and beta galactosidase, 3 enzymes involved in the metabolism of lactose in Escherichia coli. The Lac operon is a cluster of structural genes specifying the above enzymes. These genes are controlled by the co-ordinated action of cis-dominant promoter and operator regions, the activity of which is in turn determined by a repressor molecule that is specified by a separate regulator gene. Most of the detailed discovery of this system was worked out by François Jacob and Jacques Monod during the late 1950s and early 1960s; the Lac operon DNA was isolated in pure form in 1969.

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lac operon

lac operon The operon that regulates lactose metabolism in the bacterium Escherichia coli. Its form was first postulated in 1961 by François Jacob (1920– ) and Jacques Monod (1910–76) to explain control of β-galactosidase synthesis, and it is used as a model for the structure of all other operons. See Jacob–Monod hypothesis.

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"lac operon." A Dictionary of Biology. . Encyclopedia.com. 20 May. 2018 <http://www.encyclopedia.com>.

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