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bacitracin (băs´Ĭtrā´sĬn), antibiotic produced by a strain of the bacterial species Bacillus subtilis. It is widely used for topical therapy such as for skin and eye infections; it is effective against gram-positive bacteria, including strains of staphylococcus that are resistant to penicillin (see Gram's stain). Bacitracin is toxic to humans and is no longer used internally.

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bacitracin zinc (ba-si-tray-sin) n. an antibiotic effective against a number of microorganisms. Combined with other antibiotics (neomycin or polymyxin B), it is applied externally to treat infections of the skin and eyes.