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de·pres·sive / diˈpresiv/ • adj. causing feelings of hopelessness, despondency, and dejection. ∎  Med. relating to or tending to suffer from clinical depression: a depressive illness. ∎  causing a reduction in strength, effectiveness, or value: steroids have a depressive effect on the immune system. • n. Med. a person suffering from or with a tendency to suffer from depression.

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