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mo·nop·o·lize / məˈnäpəˌlīz/ • v. [tr.] (of an organization or group) obtain exclusive possession or control of (a trade, commodity, or service). ∎  have or take the greatest share of: the bigger teams monopolize the most profitable sponsorships and TV deals. ∎  get or keep exclusively to oneself: Sophie monopolized the guest of honor for most of the evening.DERIVATIVES: mo·nop·o·li·za·tion / məˌnäpələˈzāshən/·nop·o·liz·er n.