restless legs syndrome

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restless legs syndrome (Ekbom's syndrome) (rest-lis) n. a condition in which a sense of uneasiness, restlessness, and itching, often accompanied by twitching and pain, is felt in the calves of the legs when sitting or lying down, especially in bed at night. The cause is unknown: it may be inadequate circulation, peripheral neuropathy, deficiency of iron, vitamin B12, or folic acid, or a reaction to antipsychotic or antidepressant drugs.

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