disease-modifying antirheumatic drug

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disease-modifying antirheumatic drug (DMARD) (anti-roo-mat-ik) n. a drug used in the treatment of rheumatic disease that affects the progression of the disease by suppressing the disease process. DMARDs include drugs affecting the immune response (immunomodulators), such as immunosuppressants (e.g. methotrexate) and infliximab; gold salts; penicillamine; sulfasalazine; and hydroxychloroquine.