Intrinsic factor

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intrinsic factor A protein secreted in the gastric juice which is required for the absorption of vitamin B12; impaired secretion results in pernicious anaemia.

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intrinsic factor n. a glycoprotein secreted in the stomach. The secretion of intrinsic factor is necessary for the absorption of vitamin B12; a failure of secretion leads to a deficiency of the vitamin and the condition of pernicious anaemia.

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intrinsic factor See vitamin B complex.