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hepatomegaly Enlargement of the liver as a result of congestion (e.g. in heart failure), inflammation or fatty infiltration (as in kwashiorkor).

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hepatomegaly (hep-ă-toh-meg-ă-li) n. enlargement of the liver to such an extent that it can be felt below the rib margin. This may be due to congestion, inflammation, infiltration (e.g. by fat), or tumour.