J. A. Strong
J. A. Strong
American physician who with P. A. Jacobs helped show that Klinefelter's syndrome was linked to one of the sex chromosomes. This was one of the first diseases shown to be either "x-linked" or "ylinked." Linkage to a sex chromosome is important because, in males, there is only one of each sex chromosome. This means that a genetically recessive disease or trait will not appear in women but will appear in men because men lack a second x chromosome to mask the disease.
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sex chromosome , sex chromosome A chromosome whose presence or absence is linked with the sex of the bearer, and that plays a role in sex determination. It is present… Heterogametic Sex , heterogametic sex The sex that has sex chromosomes that differ in morphology (e.g. XY), and that therefore produces two different kinds of gametes wi… Sex Linkage , sex linkage The location of a gene on a sex chromosome. Such a gene is usually unrelated to primary or secondary sexual characters and is located on… dosage compensation , dosage compensation A genetic process that compensates for genes which exist in two doses in the homozygous dominants, so that the heterozygotes prod… X Chromosome , The X chromosome occupies an exceptional place in the mammalian genome . Together with the Y chromosome, the X chromosome differentiates the sexes. M… Nosology , nosology classification of diseases, XVIII. f. Gr. nósos disease; see -LOGY.
nosology (nos-ol-ŏji) n. the naming and classification of diseases.
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J. A. Strong