Groote Schuur (khrŏŏ´tə skür) [Afrik.,=large barn], estate, Cape Town, Western Cape, SW South Africa. The main building of the estate, which is a good example of Dutch colonial architecture, was erected on the site of a large barn dating from 1657. It once was the home of Cecil Rhodes and later was an official residence of South Africa's prime ministers and presidents; it is now a museum. The Univ. of Cape Town is those grounds of the estate that were bequeathed by Rhodes for a national university; in 1967, Dr. Christiaan Barnard performed the world's first human heart transplant operation there.