reverse mutation

views updated May 23 2018

reverse mutation (reversion) The production by further mutation of a premutation gene from a mutant gene. This reverse mutation restores the ability of the gene to produce a functional protein. Strictly, reversion is the correction of a mutation (i.e. it occurs at the same site); more loosely, the term is applied also to a mutation at another site that masks or suppresses the effect of the first mutation (in fact such organisms are not non-mutant, but double mutants with the same phenotype). Compare SUPPRESSOR MUTATION.

reverse mutation

views updated Jun 11 2018

reverse mutation (reversion) The production by further mutation of a premutation gene from a mutant gene. This reverse mutation restores the ability of the gene to produce a functional protein. Strictly, reversion is the correction of a mutation, i.e. it occurs at the same site; more loosely, though, the term is applied also to a mutation at another site that masks or suppresses the effect of the first mutation. (In fact, such organisms are not non-mutant, but are double mutants with the same phenotype.) Compare SUPPRESSOR MUTATION.