Such a peripheral nerve contains microscopic fibres called axons. Groups of a few axons are wrapped together in a delicate fibrous sheath, and bundles of such bundles are again enclosed in a fibrous sheath to form the whole nerve.
Axons are also known as nerve fibres. They are long processes (thin extensions from the main cell body) of neurons, the cells of the nervous system, which, to complicate things further, are also known as ‘nerve cells’. Axons conduct brief electrical pulses called ‘nerve impulses’ (technically, action potentials), which originate in the sensitive nerve endings in the skin or other tissues, or at the cell body of a neuron. Impulses convey sensory messages in these afferent fibres into the central nervous system, and motor commands in efferent fibres from central neurons out to muscles and glands throughout the body.
Axons conduct impulses at speeds from about 0.5–100 m/sec. The velocity increases with the diameter of the axon (typically between 0.1 and 2 μm) and is even further speeded up if the axon is covered (as many of them are) by insulating fatty material, called a myelin sheath. In general, axons run uninterrupted along the entire length of a peripheral nerve as well as some distance inside the central nervous system. Thus they can be extraordinarily long. For instance, sensory axons extend from the skin of the big toe to the base of the brain; and motor axons run from the motor cortex of the cerebral hemispheres right down to motor neurons at the bottom of the spinal cord.
Nerve cells share many basic features with cells elsewhere in the body. They have a cell body, with a nucleus containing genetic information, in the DNA of the chromosomes; and cytoplasm containing organelles, which are involved in metabolism and the production of specific proteins necessary for the proper functioning of the neuron; all covered with a thin membrane. They differ from other cells in having two types of fibre-like processes. The cell body is surrounded by a bush of up to ten or so dendrites (Greek dendron: wood or tree), but typically has only one axon, which may have many branches. Axons are specialized not only for the conduction of impulses but also for the secretion, at their tips, of chemical messengers that affect the cells that they contact (muscle or gland cells, or the dendrites or cell bodies of other neurons).
The junction between the terminal of an axon and the membrane of another neuron is called a synapse, with a very narrow synaptic cleft between the two. The axon terminal contains many tiny droplets called synaptic vesicles, close to the zone of contact. A chemical neurotransmitter (sometimes more than one kind) is stored in these vesicles and is released into the cleft when an action potential invades the terminal. This released transmitter then binds to receptors, specialized protein molecules in the membrane of the next cell, ultimately causing electrical excitation or inhibition of that cell. There are many different transmitters, but the most widespread excitatory ones are acetylcholine, noradrenaline, and glutamate; glycine and gamma-aminobutyric acid (GABA) are the major inhibitory transmitters.
Finally, the term ‘nerves’ has a colloquial usage, denoting anxiety or apprehension, or as an ‘explanation’ of unusual behaviour. While this adds further to the ambiguity of this over-used word, it is at least a popular recognition of the role of the nervous system in determining such ‘mental’ functions as the emotions and character.
See also grey matter; nervous system; white matter.
"nerves." The Oxford Companion to the Body. . Encyclopedia.com. (May 23, 2018). http://www.encyclopedia.com/medicine/encyclopedias-almanacs-transcripts-and-maps/nerves
"nerves." The Oxford Companion to the Body. . Retrieved May 23, 2018 from Encyclopedia.com: http://www.encyclopedia.com/medicine/encyclopedias-almanacs-transcripts-and-maps/nerves
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- a temporary paralytic or hypnotic state, often brought on by strong emotion. —cataplectic, adj.
- the state or condition of a nerve when an electric current is passing through it. —electrotonic, adj.
- a sharp and paroxysmal pain along the course of a nerve. —neuralgie, adj.
- 1. Medicine. a nervous debility and exhaustion, as from overwork or prolonged nervous strain.
- 2. popularly, a nervous breakdown, —neurasthenie, adj.
- Rare. the theory that all the body’s activity is controlled by nervous fluid.
- 1. an inflammation in a nerve.
- 2. a continuous pain in a nerve, associated with paralysis, loss of reflexes, and sensory disturbances. —neuritic, adj.
- Medicine. the branch of anatomy that studies the anatomy of the nervous system. — neuroanatomical, adj.
- the branch of neurology concerned with description of the nerves and nervous system. —neurographic, neurographical, adj.
- the branch of medical science that studies the nerves and the nervous system, especially the diseases that affect them. —neurologist, n. —neurological, adj.
- Medicine. a psychosomatic disease. —neuromimetic, adj.
- the pathology of the nervous system. —neuropathologist, n. —neuropathologic, neuropathological, adj.
- any disease or disorder of the nerves. —neuropathist, n. —neuropathie, adj.
- the branch of medicine dealing with diseases affecting the mind and the nervous system. —neuropsychiatrist, n. —neuropsychiatric, adj.
- a functional disorder of the nervous system. See also 334. PSYCHOLOGY . —neurotic, n., adj.
- the cutting of a nerve, as to relieve neuralgia. —neurotomist, n.
- neuritis that affects several or many nerves.
- neuralgia affecting the face.
- pseudesthesia, pseudaesthesia
- Pathology. false or ghost sensations, such as those which seem to come from a missing limb. —pseudesthetic, pseudaesthetic, adj.
- the surgical cutting of the nerve roots of the spine, usually the sensory or posterior roots, to relieve pain or eliminate paralysis.
"Nerves." -Ologies and -Isms. . Encyclopedia.com. (May 23, 2018). http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/nerves
"Nerves." -Ologies and -Isms. . Retrieved May 23, 2018 from Encyclopedia.com: http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/nerves