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nerve·less / ˈnərvlis/ • adj. 1. inert; lacking vigor or feeling: the knife dropped from Grant's nerveless fingers. ∎  (of literary or artistic style) diffuse or insipid: Wilde and his art are described as “nerveless and effeminate.”2. confident; not nervous: with nerveless panache.3. Anat. & Biol. lacking nerves or nervures.DERIVATIVES: nerve·less·ly adv.nerve·less·ness n.