derange

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de·range / diˈrānj/ • v. [tr.] [usu. as adj.] (deranged) cause (someone) to become insane: a deranged man. ∎  throw (something) into confusion; cause to act irregularly: stress deranges the immune system. ∎ archaic intrude on; interrupt: I am sorry to have deranged you for so small a matter. DERIVATIVES: de·range·ment n.

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derange XVIII. — F. déranger, OF. desrengier; see DE- 6, RANGE.