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trans·fix / transˈfiks/ • v. [tr.] 1. (usu. be transfixed) cause (someone) to become motionless with horror, wonder, or astonishment: he was transfixed by the pain in her face she stared at him, transfixed. 2. pierce with a sharp implement or weapon: a field mouse is transfixed by the curved talons of an owl. DERIVATIVES: trans·fix·ion / -ˈfikshən/ n.