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toot / toōt/ • n. 1. a short, sharp sound made by a horn, trumpet, or similar instrument. 2. inf. a snort of a drug, esp. cocaine. ∎  cocaine. 3. inf. a spell of drinking and lively enjoyment; a spree: a sales manager on a toot. • v. [tr.] 1. sound (a horn or similar instrument) with a short, sharp sound: behind us an impatient driver tooted a horn. ∎  [intr.] make such a sound: a car tooted at us. 2. inf. snort (cocaine). DERIVATIVES: toot·er n.