main line

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main line • n. a chief railroad line: [as adj.] a main-line station. ∎  a principal route, course, or connection: the main line of evolution. ∎  a chief road or street. ∎  inf. a principal vein as a site for a drug injection.• v. (main·line) [tr.] inf. inject (a drug) intravenously: Mariella mainlines cocaine five to seven times a day. DERIVATIVES: main·lin·er n.

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