hoo·doo / ˈhoōˌdoō/ • n. 1. voodoo; witchcraft. ∎ a run of bad luck associated with a person or activity: when is this hoodoo going to end? ∎ a person or thing that brings or causes bad luck.2. a column or pinnacle of weathered rock: a towering sandstone hoodoo.• v. (-doos, -dooed) [tr.] bewitch: she's hoodooed you. ∎ bring bad luck to: a fine player, but repeatedly hoodooed.