DNase

views updated May 29 2018

DNase (deoxyribonuclease; DNAase) An enzyme that catalyses the cleavage of DNA. DNase I is a digestive enzyme, secreted by the pancreas, that degrades DNA into shorter nucleotide fragments. Many other endonucleases and exonucleases cleave DNA, including the restriction enzymes and enzymes involved in DNA repair and replication.

DNAse

views updated May 14 2018

DNAse n. an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is administered by inhalation in the treatment of cystic fibrosis to reduce the viscosity of the sticky secretions in the lungs. Trade name: Pulmozyme.

DNase

views updated May 29 2018

DNase (or DNAase) Biochem. deoxyribonuclease