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prurigo (proor-I-goh) n. an intensely itchy eruption. Besnier's p. chronic lichenified atopic eczema. nodular p. a condition of unknown cause, usually found in atopic individuals (see atopy), in which severely itching nodules mostly occur on the distal limbs. p. of pregnancy prurigo occurring in the middle trimester of pregnancy, affecting mainly the abdomen and the extensor surfaces of the limbs. It may recur in later pregnancies.