prosthetic group

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prosthetic group A non-protein component of a conjugated protein, or the cofactor of an enzyme to which it is bound so tightly that it cannot be removed by dialysis.

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prosthetic group The non-protein component of a conjugated protein, or the cofactor of an enzyme to which it is bound so tightly that it cannot be removed by dialysis.

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prosthetic group Non‐protein part of an enzyme molecule; either a coenzyme or a metal ion. Essential for catalytic activity. The enzyme protein without its prosthetic group is the apo‐enzyme and is catalytically inactive. With the prosthetic group, it is known as the holo‐enzyme. See also enzyme activation assays.

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prosthetic group A tightly bound nonpeptide inorganic or organic component of a protein. Prosthetic groups may be lipids, carbohydrates, metal ions, phosphate groups, etc. Some coenzymes are more correctly regarded as prosthetic groups.