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pancreatic juice The alkaline digestive juice produced by the pancreas and secreted into the duodenum. It contains the inactive precursors of a number of protein digestive enzymes. Trypsinogen is activated to trypsin by enteropeptidase in the intestinal lumen; in turn, trypsin activates the other enzyme precursors: chymotrypsinogen to chymotrypsin, pro‐elastase to elastase, procarboxypeptidase to carboxypeptidase. Also contains lipase, amylase, and nucleases.