trib·u·la·tion / ˌtribyəˈlāshən/ • n. (usu. tribulations) a cause of great trouble or suffering: the tribulations of being a megastar. ∎ a state of great trouble or suffering: his time of tribulation was just beginning. ∎ (the tribulation or the Great Tribulation) Christian Theol. a period of great suffering expected during the end times.