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hypocretin (hy-poh-kree-tin) n. a neuropeptide that originates in the hypothalamus. Low levels of hypocretin in the cerebrospinal fluid are found in most patients with narcolepsy and may also be found in patients who have suffered with stroke, brain tumours, head injuries, and infections of the nervous system.

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hy·po·cre·tin / hīpəˈkrētn/ • another name for orexin.