tamoxifen
The Columbia Encyclopedia, Sixth Edition | Date: 2008
tamoxifen , synthetic hormone used in the treatment of breast cancer . Introduced in 1978, tamoxifen is used to prevent recurrences of cancer in women who have already undergone surgery to remove their tumors. In 1998, a large study of healthy women at high risk for breast cancer showed that tamoxifen can also prevent first occurrence of the disease: women who took the drug had a 45% lower incidence of cancer that those who received a placebo. However, adverse effects (including uterine cancer) and other concerns await further study.
Author not available, TAMOXIFEN.,
The Columbia Encyclopedia, Sixth Edition 2008
The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press
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Tamoxifen Definition Tamoxifen (also known as Nolvadex) is a synthetic compound similar to estrogen ... uterus, but blocks the effects of estrogen on breast tissue. Purpose Tamoxifen is used as adjuvant hormonal therapy immediately after surgery in ...
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tamoxifen
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... women at high risk. The most serious side effect is an increased risk of thrombosis , which may require patients to take an anticoagulant as well. Studies on its effectiveness against breast and other cancers continue. tamoxifen tamoxifen tamoxifen
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