Skip to main content
Select Source:

glucagon

glucagon (glōō´kəgŏn), hormone secreted by the α cells of the islets of Langerhans, specific groups of cells in the pancreas. It tends to counteract the action of insulin, i.e., it raises the concentration of glucose in the blood. Glucagon was first purified and crystallized in 1955; the amino acid sequence of this 29-amino acid polypeptide (see peptide) was published in 1956–57. One of the most important actions of glucagon is the promotion of glycogenolysis, i.e., the degradation of glycogen to glucose, in the liver. Glucagon stimulates adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate to 3′5′-cyclic adenosine monophosphate (cyclic AMP).

Cite this article
Pick a style below, and copy the text for your bibliography.

  • MLA
  • Chicago
  • APA

"glucagon." The Columbia Encyclopedia, 6th ed.. . Encyclopedia.com. 21 Aug. 2017 <http://www.encyclopedia.com>.

"glucagon." The Columbia Encyclopedia, 6th ed.. . Encyclopedia.com. (August 21, 2017). http://www.encyclopedia.com/reference/encyclopedias-almanacs-transcripts-and-maps/glucagon

"glucagon." The Columbia Encyclopedia, 6th ed.. . Retrieved August 21, 2017 from Encyclopedia.com: http://www.encyclopedia.com/reference/encyclopedias-almanacs-transcripts-and-maps/glucagon

glucagon

glucagon A polypeptide hormone secreted by the alpha-cells of the islets of Langerhans in the pancreas. By stimulating glycogenolysis (the breakdown of glycogen to glucose in the liver), it increases the level of glucose in the blood. Thus its function is antagonistic to insulin.

Cite this article
Pick a style below, and copy the text for your bibliography.

  • MLA
  • Chicago
  • APA

"glucagon." A Dictionary of Zoology. . Encyclopedia.com. 21 Aug. 2017 <http://www.encyclopedia.com>.

"glucagon." A Dictionary of Zoology. . Encyclopedia.com. (August 21, 2017). http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/glucagon

"glucagon." A Dictionary of Zoology. . Retrieved August 21, 2017 from Encyclopedia.com: http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/glucagon

glucagon

glucagon A hormone, secreted by the α (or A) cells of the islets of Langerhans in the pancreas, that increases the concentration of glucose in the blood by stimulating the metabolic breakdown of glycogen. It thus antagonizes the effects of insulin (see antagonism).

Cite this article
Pick a style below, and copy the text for your bibliography.

  • MLA
  • Chicago
  • APA

"glucagon." A Dictionary of Biology. . Encyclopedia.com. 21 Aug. 2017 <http://www.encyclopedia.com>.

"glucagon." A Dictionary of Biology. . Encyclopedia.com. (August 21, 2017). http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/glucagon-0

"glucagon." A Dictionary of Biology. . Retrieved August 21, 2017 from Encyclopedia.com: http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/glucagon-0

glucagon

glucagon A hormone secreted by the α‐cells of the pancreas which causes an increase in blood sugar by increasing the breakdown of liver glycogen and stimulating the synthesis of glucose from amino acids.

Cite this article
Pick a style below, and copy the text for your bibliography.

  • MLA
  • Chicago
  • APA

"glucagon." A Dictionary of Food and Nutrition. . Encyclopedia.com. 21 Aug. 2017 <http://www.encyclopedia.com>.

"glucagon." A Dictionary of Food and Nutrition. . Encyclopedia.com. (August 21, 2017). http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/glucagon

"glucagon." A Dictionary of Food and Nutrition. . Retrieved August 21, 2017 from Encyclopedia.com: http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/glucagon

glucagon

glu·ca·gon / ˈgloōkəˌgän/ • n. Biochem. a hormone formed in the pancreas that promotes the breakdown of glycogen to glucose in the liver.

Cite this article
Pick a style below, and copy the text for your bibliography.

  • MLA
  • Chicago
  • APA

"glucagon." The Oxford Pocket Dictionary of Current English. . Encyclopedia.com. 21 Aug. 2017 <http://www.encyclopedia.com>.

"glucagon." The Oxford Pocket Dictionary of Current English. . Encyclopedia.com. (August 21, 2017). http://www.encyclopedia.com/humanities/dictionaries-thesauruses-pictures-and-press-releases/glucagon

"glucagon." The Oxford Pocket Dictionary of Current English. . Retrieved August 21, 2017 from Encyclopedia.com: http://www.encyclopedia.com/humanities/dictionaries-thesauruses-pictures-and-press-releases/glucagon

glucagon

glucagon (gloo-kă-gon) n. a hormone, produced by the pancreas, that causes an increase in the blood sugar level. Glucagon is administered by injection to counteract diabetic hypoglycaemia.

Cite this article
Pick a style below, and copy the text for your bibliography.

  • MLA
  • Chicago
  • APA

"glucagon." A Dictionary of Nursing. . Encyclopedia.com. 21 Aug. 2017 <http://www.encyclopedia.com>.

"glucagon." A Dictionary of Nursing. . Encyclopedia.com. (August 21, 2017). http://www.encyclopedia.com/caregiving/dictionaries-thesauruses-pictures-and-press-releases/glucagon

"glucagon." A Dictionary of Nursing. . Retrieved August 21, 2017 from Encyclopedia.com: http://www.encyclopedia.com/caregiving/dictionaries-thesauruses-pictures-and-press-releases/glucagon