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MICHAEL ALLABY. "ligase." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. 10 Feb. 2010 <http://www.encyclopedia.com>.
MICHAEL ALLABY. "ligase." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. (February 10, 2010). http://www.encyclopedia.com/doc/1O7-ligase.html
MICHAEL ALLABY. "ligase." A Dictionary of Plant Sciences. 1998. Retrieved February 10, 2010 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O7-ligase.html
(Including press releases, facts, information, and biographies)
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Rigel Announces Publications Highlighting Two New Screening Mechanisms for...
PR Newswire November 3, 2005 700+ words Receives Patents Broadly Covering Ligase Screening Methodologies SOUTH SAN FRANCISCO...Volume 399) relating to its ubiquitin ligase program. Ubiquitin ligases are enzymes...promoting complex (APC), an E3 ubiquitin ligase under scrutiny as an anti-cancer target... |
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Ligase Chain Reaction a Sensitive Tool for Primary Screening.
Newspaper article from: TB & Outbreaks Week January 16, 2001 700+ words ...published in the journal Thorax says that ligase chain reaction is a valuable primary screening...be M. tuberculosis-positive based on ligase chain reaction screening. Thirty-two...culture and smear tests along with the ligase chain reaction assays. "In the newly... |
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Binding of Nucleotides by T4 DNA ligase and T4 RNA ligase: Optical absorbance...
Magazine article from: Biophysical Journal Cherepanov, Alexei V; de Vries, Simon December 1, 2001 700+ words ...with the exocyclic amino group. T4 DNA ligase is shown to have, besides the catalytic...residue is located in the active site of the ligase. The decrease of absorbance around 298...tryptophan residue are weakened in the ligase-nucleotide complex. The excitation... |
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Rigel Granted Key Patents in Ubiquitin Ligase Field.
PR Newswire June 9, 2004 700+ words ...identifying and/or measuring E3 ubiquitin ligase activity and screening for agents that...characterizing and exploiting the ubiquitin ligase system for the discovery of potentially...broadest efforts, working on numerous ligase targets. Rigel was one of the first companies... |
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Rigel Ubiquitin Ligase Program Identifies Molecules With Anti-HIV Activity.
PR Newswire March 27, 2007 700+ words ...recruiting Apobec3G into an ubiquitin ligase complex, Vif enables the subsequent degradation...modulating the intracellular ubiquitin ligase signaling pathways utilized by Vif so...fight the virus by means of a ubiquitin ligase target. By focusing on a host target... |
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Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex...
Magazine article from: Plant Cell Chen, Haodong; Shen, Yunping; Tang, Xiaobo; Yu, Lu; Et al August 1, 2006 700+ words ...subunit to form an active E3 ubiquitin ligase both in vivo and in vitro. The partial...Therefore, this CUL4-based E3 ligase is essential for the repression of photomorphogenesis. This CUL4-based E3 ligase appears to associate physically with... |
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Modulation of Ubc4p/Ubc5p-Mediated Stress Responses by the...
Magazine article from: Genetics Mulder, Klaas W; Inagaki, Akiko; Cameroni, Elisabetta; Mousson, Florence; Et al May 1, 2007 700+ words ...CNOT4, displays UbcH5B-dependent ubiquitin-protein ligase (E3 ligase) activity in a reconstituted in vitro system. However...purified Ccr4-Not complexes showed Not4p-mediated E3 ligase activity, which was dependent on the interaction with... |
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Celgene Scientists Will Present Data at Ubiquitin Ligase Conference.
PR Newswire June 11, 2002 700+ words ...24-25, 2002 Comprehensive Ubiquitin Ligase Website Launched WARREN, N.J., June...data on the Company's novel ubiquitin ligase modulators will be presented at the first...Celgene has launched http://www.ligase.com. The website provides the scientific... |
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Preclinical Data Demonstrate Celgene Small Molecule P27 Ligase Modulator...
PR Newswire November 21, 2002 700+ words ...Company's novel, small molecule p27 ligase modulator promotes apoptosis (cell death...that our proprietary, small molecule p27 ligase modulators may be important anti-cancer...Division. "We are advancing our ubiquitin ligase modulator development program to understand... |
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SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to...
Magazine article from: Cell Division Barbash, Olena Lin, Douglas I. Diehl, J. Alan January 1, 2007 700+ words ...degradation, the putative E3 ubiquitin ligase, has remained obscure. In a recent report...sup.Fbx4/[alpha]B-crystallin] ligase will allow new experimental approaches...E2 together with the E3, or ubiquitin ligase, attaches ubiquitin molecules to target... |
For more facts and information, see all related premium articles
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ligase
Book article from: A Dictionary of Biology ligase Any of a class of enzymes that catalyse the formation of covalent bonds using...synthesis and repair of many biological molecules, including DNA (see DNA ligase ), and are used in genetic engineering to insert foreign DNA into cloning... |
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DNA ligase
Book article from: A Dictionary of Biology DNA ligase An enzyme that is able to join together two portions of DNA and therefore plays an important role in DNA repair . DNA ligase is also used in recombinant DNA technology (see genetic engineering ) as it ensures that the foreign DNA (e... |
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Recombinant DNA Molecules
Book article from: World of Microbiology and Immunology ...segments of DNA to be isolated. Insertion of the isolated DNA into the recipient genome is done using an enzyme called DNA ligase. Typically, the recombinant DNA forms part of the DNA making up a plasmid. The mobility of the plasmid facilitates the easy... |
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Recombinant DNA
Book article from: Genetics ...with the same restriction enzyme. The two DNAs are then mixed together and joined, this time using an enzyme called DNA ligase, to make an intact, double-stranded DNA molecule. This construct is then put into Escherichia coli cells, where the resulting... |
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discontinuous replication
Book article from: A Dictionary of Biology ...eukaryotes and 1000–2000 nucleotides in prokaryotes. The fragments are then covalently bound together by the enzyme DNA ligase , forming a continuous chain of nucleotides, thus completing replication of the lagging strand. See also DNA replication... |
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