Research topic:growth hormone

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growth hormone

A Dictionary of Biology | 2004 | © A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

growth hormone (GH; somatotrophin) A hormone, secreted by the mammalian pituitary gland, that stimulates protein synthesis and growth of the long bones in the legs and arms. It also promotes the breakdown and use of fats as an energy source, rather than glucose. Production of growth hormone is greatest during early life. Its secretion is controlled by the opposing actions of two hormones from the hypothalamus: growth hormone releasing hormone (somatoliberin), which promotes its release; and somatostatin, which inhibits it. Overproduction of human growth hormone (hGH) results in gigantism in childhood and acromegaly in adults; underproduction results in dwarfism. Bovine somatotrophin (BST) has been used to increase milk and meat production in cattle.

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