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genetic code

A Dictionary of Biology | 2004 | © A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

genetic code The means by which genetic information in DNA controls the manufacture of specific proteins by the cell. The code takes the form of a series of triplets of bases in DNA, from which is transcribed a complementary sequence of codons in messenger RNA (see transcription). The sequence of these codons determines the sequence of amino acids during protein synthesis. There are 64 possible codes from the combinations of the four bases present in DNA and messenger RNA and 20 amino acids present in body proteins: some of the amino acids are coded by more than one codon, and some codons have other functions (see start codon; stop codon).

First base in codon

Second base in codon

Third base in codon

The genetic code

U

C

A

G

U

UUU Phe

UCU Ser

UAU Tyr

UGU Cys

U

UUC Phe

UCC Ser

UAC Tyr

UGC Cys

C

UUA Leu

UCA Ser

UAA (stop codon)

UGA (stop codon)

A

UUG Leu

UCG Ser

UAG (stop codon)

UGG Trp

G

C

CUU Leu

CCU Pro

CAU His

CGU Arg

U

CUC Leu

CCC Pro

CAC His

CGC Arg

C

CUA Leu

CCA Pro

CAA Gln

CGA Arg

A

CUG Leu

CCG Pro

CAG Gln

CGG Arg

G

A

AUU Ile

ACU Thr

AAU Asn

AGU Ser

U

AUC Ile

ACC Thr

AAC Asn

AGC Ser

C

AUA Ile

ACA Thr

AAA Lys

AGA Arg

A

AUG Met (start codon)

ACG Thr

AAG Lys

AGG Arg

G

G

GUU Val

GCU Ala

GAU Asp

GGU Gly

U

GUC Val

GCC Ala

GAC Asp

GGC Gly

C

GUA Val

GCA Ala

GAA Glu

GGA Gly

A

GUG Val

GCG Ala

GAG Glu

GGG Gly

G


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