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wobble hypothesis
wobble hypothesis A theory to explain the partial degeneracy of the genetic code due to the fact that some t-RNA molecules can recognize more than one codon. The theory proposes that the first two bases in the codon and anticodon will form complementary pairs in the normal antiparallel fashion. However, a degree of steric freedom or ‘wobble’ is allowed in the base-pairing at the third position. Thus, for serine, six m-RNA codons may be paired with only three t-RNA anticodons.
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Cite this article
MICHAEL ALLABY. "wobble hypothesis." A Dictionary of Zoology. 1999. Encyclopedia.com. 31 May. 2012 <http://www.encyclopedia.com>. MICHAEL ALLABY. "wobble hypothesis." A Dictionary of Zoology. 1999. Encyclopedia.com. (May 31, 2012). http://www.encyclopedia.com/doc/1O8-wobblehypothesis.html MICHAEL ALLABY. "wobble hypothesis." A Dictionary of Zoology. 1999. Retrieved May 31, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O8-wobblehypothesis.html |
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wobble hypothesis
wobble hypothesis A theory proposed to explain the partial degeneracy of the genetic code in that some t-RNA molecules can recognize more than one codon. It is proposed that the first 2 bases in the codon and anticodon will form complementary pairs in the normal antiparallel fashion. However, a degree of steric freedom or ‘wobble’ is allowed in the base pairing at the third position. Thus, for serine, 6 m-RNA codons may be paired with only 3 t-RNA anticodons.
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Cite this article
MICHAEL ALLABY. "wobble hypothesis." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. 31 May. 2012 <http://www.encyclopedia.com>. MICHAEL ALLABY. "wobble hypothesis." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. (May 31, 2012). http://www.encyclopedia.com/doc/1O7-wobblehypothesis.html MICHAEL ALLABY. "wobble hypothesis." A Dictionary of Plant Sciences. 1998. Retrieved May 31, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O7-wobblehypothesis.html |
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