thymine

thymine

thymine , organic base of the pyrimidine family. Thymine was the first pyrimidine to be purified from a natural source, having been isolated from calf thymus and beef spleen in 1893-4. The accepted structure of the thymine molecule was published in 1900; this structure was confirmed when several investigators reported the synthesis of the compound during the period 1901 to 1910. Combined with the sugar deoxyribose in a glycosidic linkage, thymine forms a derivative called thymidine (a nucleoside), which in turn can be phosphorylated with from one to three phosphoric acid groups, yielding respectively the three nucleotides TMP (thymidine monophosphate), TDP (thymidine diphosphate), and TTP (thymidine triphosphate). The analogous nucleosides and nucleotides formed from thymine and ribose occur only very rarely in living systems; such is not the case with the other pyrimidines. The nucleotide derivatives of thymine do not exhibit as much activity as coenzymes , although TTP can readily donate one of its phosphate groups to adenosine diphosphate (ADP) to form adenosine triphosphate (ATP), an extremely important intermediate in the transfer of chemical energy in living systems. Since the thymine nucleotides contain only deoxyribose and not ribose, TTP is the source of thymidine only in deoxyribonucleic acid (DNA); there is no thymine in ribonucleic acid (RNA). Thymidine is significant because of its involvement in the biosynthesis of DNA and in the preservation and transfer of genetic information. See nucleic acid .

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"thymine." The Columbia Encyclopedia, 6th ed.. 2008. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

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thymine

thy·mine / ˈ[unvoicedth]īˌmēn; -min/ • n. Biochem. a compound, C5H6N2O2, that is one of the four constituent bases of nucleic acids. A pyrimidine derivative, it is paired with adenine in double-stranded DNA.

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"thymine." The Oxford Pocket Dictionary of Current English. 2009. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

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thymine

thymine (th'y-meen) n. one of the nitrogen-containing bases (see pyrimidine) occurring in the nucleic acid DNA.

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"thymine." A Dictionary of Nursing. 2008. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

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thymine

thymine A pyrimidine derivative and one of the major component bases of nucleotides and the nucleic acid DNA.

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"thymine." A Dictionary of Biology. 2004. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

"thymine." A Dictionary of Biology. 2004. Encyclopedia.com. (February 10, 2012). http://www.encyclopedia.com/doc/1O6-thymine.html

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thymine

thymine A pyrimidinebase found in nucleic acids.

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MICHAEL ALLABY. "thymine." A Dictionary of Ecology. 2004. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

MICHAEL ALLABY. "thymine." A Dictionary of Ecology. 2004. Encyclopedia.com. (February 10, 2012). http://www.encyclopedia.com/doc/1O14-thymine.html

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thymine

thymine The pyrimidine base that occurs in DNA.

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MICHAEL ALLABY. "thymine." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

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thymine

thymine A pyrimidine base that occurs in DNA.

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MICHAEL ALLABY. "thymine." A Dictionary of Zoology. 1999. Encyclopedia.com. 10 Feb. 2012 <http://www.encyclopedia.com>.

MICHAEL ALLABY. "thymine." A Dictionary of Zoology. 1999. Encyclopedia.com. (February 10, 2012). http://www.encyclopedia.com/doc/1O8-thymine.html

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Free newspaper and magazine articles

A DFT study of thymine and its tautomers.(discrete Fourier transform)(Report)
Magazine article from: Canadian Journal of Chemistry; 2/1/2009
Role of thymine in protein coding frames of mRNA sequences.(Hypothesis)
Magazine article from: Bioinformation; 1/1/2008
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Magazine article from: Canadian Journal of Microbiology; 4/1/2007

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