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streptomycin

The Columbia Encyclopedia, Sixth Edition
streptomycin , antibiotic produced by soil bacteria of the genus Streptomyces and active against both gram-positive and gram-negative bacteria (see Gram's stain ), including species resistant to other antibiotics, e.g., some streptococci, penicillin-resistant staphylococci, and bacteria of the genera Proteus and Pseudomonas. Originally isolated by Selman A. Waksman and Albert Schatz in 1947, streptomycin is effective against tubercle bacilli and is a mainstay of tuberculosis therapy. Because streptomycin-resistant tubercle bacilli emerge during treatment, the antibiotic is usually... Read more
Streptomyces
The Columbia Encyclopedia, Sixth Edition

Streptomyces , bacterial genus of the order Actinomycetales, members of which resemble fungi in their branching filamentous structure. Various species produce such antibiotics as streptomycin and various tetracyclines .

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streptomycin
A Dictionary of Nursing streptomycin (strep-toh- my -sin) n. an aminoglycoside antibiotic, derived from the bacterium Streptomyces griseus, that is used in combination with other drugs for treating tuberculosis and brucellosis. It is administered by intramuscular injection. Read more

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Effect of streptomycin on the active force of bioengineered heart muscle in response to controlled stretch
Magazine article from: In Vitro Cellular & Developmental Biology; 7/1/2008; ; 700+ words ; ...muscle (BEHMs) and test the system when streptomycin (an aminoglycoside antibiotic, which...or excluded from the culture medium. Streptomycin is a very commonly used component of...applied mechanical stretch protocol when streptomycin is present in the culture medium, but... Read more
ALBERT SCHATZ, EDUCATOR, MICROBIOLOGIST, STREPTOMYCIN DISCOVERER 1920 - 2005
Magazine article from: BioCycle; 2/1/2005; ; 333 words ; ...1940s helped develop the antibiotic streptomycin and was Professor Emeritus of Temple...Rutgers University when he discovered streptomycin, the first effective treatment for...50th anniversary of the discovery of streptomycin, Dr. Schatz was awarded the Rutgers... Read more
Microbiologist Albert Schatz, 84, Discovered Streptomycin
Newspaper article from: Jewish Exponent; 2/17/2005; 231 words ; ...and co-discoverer of the antibiotic streptomycin for the treatment of tuberculosis...A. Waksman, Schatz discovered that streptomycin was effective against tuberculosis...Waksman share a 1948 U.S. patent for streptomycin. Schatz continued to do research throughout... Read more
Health fears over resistant bacteria; STREPTOMYCIN USE
Newspaper article from: The Press; 12/10/2007; ; 514 words ; ...tested had intermediate resistance to streptomycin, from the same family of antibiotics. Streptomycin is not used by the poultry industry...seedlings. Millar said the discovery of streptomycin resistance in the chicken indicated... Read more
The Discovery of Streptomycin
Magazine article from: The Scientist; 8/1/2007; ; 414 words ; ...with nutrient formulas for growing streptomycin-producing cultures. By fall 1943, Waksman...Albert Schatz. Schatz soon isolated streptomycin, an aminoglycoside that inhibits protein...November 1944 and February 1945. She was streptomycin's first success against TB.2 The US... Read more
CDC recommends four-drug treatment of tuberculosis in multidrug-resistant era. (Centers for Disease Control and Prevention, isoniazid, rifampin, pyrazinamide, ethambutol or streptomycin)
Magazine article from: American Family Physician; 9/15/1993; 700+ words ; ...include isoniazid, rifampin, pyrazinamide, and ethambutol or streptomycin. When drug-susceptibility results are available, the regimen...should be discontinued after eight weeks, but ethambutol or streptomycin should be continued (along with isoniazid and rifampin) for... Read more
Current trends in chemotherapy of tuberculosis
Magazine article from: Indian Journal of Medical Research; 10/1/2004; ; 700+ words ; After streptomycin, which heralded the era of antibacterial...It was no longer necessary to give streptomycin daily for three months initially...only in 1944 with the discovery of streptomycin by Selman Waksman1,2. Before that... Read more
Audiologic features of hearing loss due to the 1,555 mutation of mitochondrial DNA
Magazine article from: The Annals of Otology, Rhinology & Laryngology; 8/1/1997; ; 700+ words ; ...each of three families with familial streptomycin hearing loss, and report the pedigrees...mitochondrial DNA, sensorineural hearing loss, streptomycin. INTRODUCTION The characteristics of...suggested that since many cases of familial streptomycin hearing loss were occurring by maternal... Read more
Apple pests stand up to antibiotics.(drug resistant bacteria found in orchards)(Brief Article)
Magazine article from: Science News; 3/18/2000; ; 279 words ; ...Resistance to the common antibiotic streptomycin is sweeping through apple and pear orchards...farmers spray more than 11,000 kilograms of streptomycin on U.S. orchards every spring. Streptomycin and the antibiotic oxytetracycline both... Read more
Evaluation of the BBL MGIT (mycobacterial growth indicator tube) AST SIRE system for antimycobacterial susceptibility testing of Mycobacterium tuberculosis to 4 primary antituberculous drugs
Magazine article from: Archives of Pathology & Laboratory Medicine; 1/1/2000; ; 700+ words ; ...proportion), rifampin, ethambutol, and streptomycin. Design.-Thirty-one clinical isolates...for ethambutol,and 100% and 100% for streptomycin, excluding the isolate for which the discordant streptomycin result could not be resolved. For... Read more

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