streptomycin

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streptomycin

streptomycin , antibiotic produced by soil bacteria of the genus Streptomyces and active against both gram-positive and gram-negative bacteria (see Gram's stain ), including species resistant to other antibiotics, e.g., some streptococci, penicillin-resistant staphylococci, and bacteria of the genera Proteus and Pseudomonas. Originally isolated by Selman A. Waksman and Albert Schatz in 1947, streptomycin is effective against tubercle bacilli and is a mainstay of tuberculosis therapy. Because streptomycin-resistant tubercle bacilli emerge during treatment, the antibiotic is usually used in combination with one or more of the drugs isoniazid , ethambutol, and aminosalicylic acid. Streptomycin acts by inhibiting protein synthesis and damaging cell membranes in susceptible microorganisms. Possible side effects include injury to the kidneys and nerve damage that can result in dizziness and deafness.

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streptomycin

A Dictionary of Nursing | 2008 | Â© A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

streptomycin (strep-toh-my-sin) n. an aminoglycoside antibiotic, derived from the bacterium Streptomyces griseus, that is used in combination with other drugs for treating tuberculosis and brucellosis. It is administered by intramuscular injection.

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A Dictionary of Biology | 2004 | Â© A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

streptomycin See Actinobacteria; antibiotics.

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	Transferable Plasmid-Mediated Resistance to Streptomycin in a Clinical Isolate of Yersinia pestis. Magazine article from: Emerging Infectious Diseases; 1/1/2001
	Molecular identification of streptomycin monoresistant mycobacterium tuberculosis related to multidrug-resistant W strain. (Research). Magazine article from: Emerging Infectious Diseases; 9/1/2001
	Mycobacterium tuberculosis drug resistance, Ghana.(Letter to the editor) Magazine article from: Emerging Infectious Diseases; 7/1/2006

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	PFIZER BEGINS FREE DISTRIBUTION OF STREPTOMYCIN; ANTIBIOTIC HELPS COMBAT SPREAD OF MULTIPLE-DRUG-RESISTANT STRAINS OF TUBERCULOSIS PR Newswire; 7/8/1993; 700+ words ; ...today that it has begun distributing streptomycin to physicians throughout the country...combination with other medicines, streptomycin can be used for treating the growing...in 40 percent or more of all cases. Streptomycin had been a widely used antibiotic in...
	Effect of streptomycin on the active force of bioengineered heart muscle in response to controlled stretch Magazine article from: In Vitro Cellular & Developmental Biology; 7/1/2008; ; 700+ words ; ...BEHMs) and test the system when streptomycin (an aminoglycoside antibiotic, which...excluded from the culture medium. Streptomycin is a very commonly used component of...applied mechanical stretch protocol when streptomycin is present in the culture medium...
	The Discovery of Streptomycin Magazine article from: The Scientist; 8/1/2007; ; 640 words ; ...with nutrient formulas for growing streptomycin-producing cultures. By fall 1943...Albert Schatz. Schatz soon isolated streptomycin, an aminoglycoside that inhibits protein...November 1944 and February 1945. She was streptomycin's first success against TB.2 The...
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	Health fears over resistant bacteria; STREPTOMYCIN USE Newspaper article from: The Press; 12/10/2007; ; 700+ words ; ...tested had intermediate resistance to streptomycin, from the same family of antibiotics. Streptomycin is not used by the poultry industry...seedlings. Millar said the discovery of streptomycin resistance in the chicken indicated...
	Transferable Plasmid-Mediated Resistance to Streptomycin in a Clinical Isolate of Yersinia pestis. Magazine article from: Emerging Infectious Diseases; 1/1/2001; ; 700+ words ; ...strain with high-level resistance to streptomycin, isolated from a human case of bubonic...species. Emergence of resistance to streptomycin in Y. pestis represents a critical...attributable to inadequate surveillance. Streptomycin, chloramphenicol, and tetracycline...
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