scopolamine

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scopolamine

scopolamine or hyoscine , alkaloid drug obtained from plants of the nightshade family (Solanaceae), chiefly from henbane , Hyoscyamus niger. Structurally similar to the nerve substance acetylcholine , scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system and produces symptoms typical of parasympathetic system depression: dilated pupils, rapid heartbeat, and dry skin, mouth, and respiratory passages. Because scopolamine depresses the central nervous system, it is used as a sedative prior to anesthesia and as an antispasmodic in certain disorders characterized by restlessness and agitation, e.g., delirium tremens, psychosis, mania, and Parkinsonism. When combined with morphine , the effect produced is a tranquilized state known as twilight sleep; this combination of drugs was formerly used in obstetrics but is now considered too dangerous. Overdosage of scopolamine causes delirium, delusions, paralysis, and stupor. The alkaloid is found in a variety of nonprescription sedatives.

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"scopolamine." The Columbia Encyclopedia, Sixth Edition. 2008. Encyclopedia.com. 22 Dec. 2009 <http://www.encyclopedia.com>.

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scopolamine

A Dictionary of Nursing | 2008 | Â© A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

scopolamine (skŏ-pol-ă-meen) n. see hyoscine.

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scopolamine

The Oxford Pocket Dictionary of Current English | 2009 | © The Oxford Pocket Dictionary of Current English 2009, originally published by Oxford University Press 2009. (Hide copyright information) Copyright

sco·pol·a·mine / skəˈpäləˌmēn/ • n. Chem. a poisonous plant alkaloid, C₁₇H₂₁NO₄, used to counter motion sickness and as a preoperative medication for examination of the eye. It is obtained chiefly from plants of the nightshade family (esp. genus Scopolia).

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Free newspaper and magazine articles

	Intranasal Scopolamine for Motion Sickness: SCHWARZ PHARMA Sells Rights to Nastech Pharmaceutical. Business Wire; 12/17/1999
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