phenolphthalein

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phenolphthalein

The Columbia Encyclopedia, Sixth Edition | 2008 | The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information) Copyright

phenolphthalein , or 2,2-Bis( p -hydroxyphenyl) phthalide, C 20 H 14 O 4 , crystalline organic compound. It is used medicinally as a laxative and is widely employed in the laboratory as an indicator of the acidity or basicity of solutions. In pure water it is insoluble, but it is soluble in basic solutions or in ethanol or acetone. In a solution with p H greater than 8 ( p H 8 is mildly basic) phenolphthalein is pink to red in color, but at p H less than 8 it is colorless. Phenolphthalein is a phenol derivative of phthalic anhydride.

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phenolphthalein

A Dictionary of Biology | 2004 | © A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

phenolphthalein A dye used as an acid-base indicator. It is colourless below pH 8 and red above pH 9.6. It is used in titrations involving weak acids and strong bases. It is also used as a laxative.
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Schering-Plough HealthCare Products: FDA Announces Proposal to Reclassify Widely Used Stimulant Laxative Ingredient Phenolphthalein as Unsafe
PR Newswire; 8/29/1997; 700+ words ; ...September 2 proposing to reclassify phenolphthalein to Category II status, defined as...Assessment Committee on April 30 that phenolphthalein is a relevant carcinogenic risk for...FEEN-A-MINT(R) do not contain phenolphthalein. Instead, these products contain...
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EX-LAX YANKED FROM SHELVES FDA PLANS TO BAN PHENOLPHTHALEIN.(BUSINESS)
Newspaper article from: The Cincinnati Post (Cincinnati, OH); 8/30/1997; 687 words ; ...it believes the ingredient phenolphthalein is safe, but that it would...that it has no reports that phenolphthalein has caused cancer in people...FDA said animal studies found phenolphthalein, at high doses, could damage...
SENOKOT LAXATIVES DO NOT CONTAIN PHENOLPHTHALEIN
PR Newswire; 12/7/1995; 586 words ; ...not contain the active ingredient phenolphthalein which has been the focus of attention...was prompted by an animal study of phenolphthalein recently released by the U.S. Public...products, which do not contain phenolphthalein. In 40 years of extensive clinical...
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Magazine article from: Drug Topics; 2/15/1999; ; 254 words ; The FDA has banned the use of phenolphthalein in OTC laxatives because of its carcinogenic potential. On Jan. 29, the agency also formally withdrew approval of danthron, another OTC laxative ingredient that has been off the market for more than 10 years.
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Magazine article from: Polymer Engineering and Science; 4/1/1995; ; 700+ words ; INTRODUCTION Owing to both scientific and technical interest, blends of a thermotropic liquid crystalline polymer (LCP) with thermoplastics have received considerable attention in the last decade. Examples of such polymer blends have been reviewed by D. Dutta et al. (1). The main purpose of
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