notochord

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notochord

The Columbia Encyclopedia, Sixth Edition | 2008 | The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information) Copyright

notochord , in biology, supporting rod running most of the length of animals of the phylum Chordata and present at varying times in the life cycle. Composed of large cells packed within a firm connective tissue sheath, the notochord lies between the neural tube (spinal cord) and the gut. The division of the phylum Chordata into subphyla is based on the structure of the notochord and the time of life in which it is present: In the subphylum Urochordata (tunicates) the notochord characterizes the larval, swimming, stage of the animals and does not extend into the head; in the subphylum Cephalochordata (lancelets) the notochord extends to the extreme tip of the head in both young and adults; and in the subphylum Vertebrata the notochord becomes surrounded by skeletal vertebrae during embryonic development—in higher vertebrates it is present in the early embryo only and is later completely replaced by the vertebrae.

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notochord

World Encyclopedia | 2005 | © World Encyclopedia 2005, originally published by Oxford University Press 2005. (Hide copyright information) Copyright

notochord In chordates, such as acorn worms, and the early embryonic stages of vertebrates, the flexible, primitive backbone; in mature vertebrates it is replaced by the spine.

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notochord

A Dictionary of Zoology | 1999 | | © A Dictionary of Zoology 1999, originally published by Oxford University Press 1999. (Hide copyright information) Copyright

notochord (chorda dorsalis) A some what flexible, rod-like structure, composed of disc-like, turgid cells, which extends virtually the entire length of the body of adult and/or larval members of the phylum Chordata. Lying below the nerve cord, but dorsal to the intestine, the notochord provides a form of flexible support to the body. In vertebrates the notochord is replaced wholly or partly by the vertebral column, but it is retained throughout life in Cephalochordata and Agnatha.

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MICHAEL ALLABY. "notochord." A Dictionary of Zoology. 1999. Encyclopedia.com. 26 Nov. 2009 <http://www.encyclopedia.com>.

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Continued growth and cell proliferation into adulthood in the notochord of the appendicularian Oikopleura dioica.(Author abstract)
Magazine article from: The Biological Bulletin; 2/1/2008; ; 700+ words ; ...region and a motile tail containing a notochord and a dorsal nerve cord (Katz, 1983...loss of tail structures, including the notochord. The salps and doliolids (Thaliacea...undergo a metamorphosis through which the notochord (if initially formed at all) is lost...
A high-affinity hemoglobin is expressed in the notochord of amphioxus, Branchiostoma californiense.
Magazine article from: The Biological Bulletin; 12/1/1998; ; 700+ words ; ...occurs at 500 nm in the in situ notochord and in vitro myotome spectra...for crude protein extract from notochords is shown in Figure 2A and from...protein peaks are evident. For both notochord and myotome extracts, the first...
The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish.(Research article)
Magazine article from: BMC Developmental Biology; 4/17/2008; ; 700+ words ; ...where U0126 treatment blocked differentiation of mesenchyme, secondary muscle and neural tissues and formation of the notochord (NC) [27, 28, 29]. The NC serves as the most important skeletal structure in lower chordates and plays an essential...
A Novel Murine Gene, Sickle tail, Linked to the Danforth's short tail Locus, Is Required for Normal Development of the Intervertebral Disc
Magazine article from: Genetics; 1/1/2006; ; 700+ words ; ...of a reporter gene was detected in the notochord during embryogenesis and in the nucleus...the third intron of the Skt gene. THE notochord is an integral component of the axial...CHIANG et eZ.1996). In addition, the notochord has major roles in vertebral column formation...
Mechanisms of specification in ascidian embryos.(Genetic Regulatory Networks in Embryogenesis and Evolution)
Magazine article from: The Biological Bulletin; 12/1/1998; ; 700+ words ; ...nerve cord, endoderm, mesenchyme, notochord, and muscle (2). The lineage of these...initiation site (9). Specification of notochord Recent studies have revealed an important...tissue. Differentiation of ascidian notochord cells is induced during the early phase...
New developmental biology study findings have been reported by T.A. Hawkins and co-researchers.
Newspaper article from: Life Science Weekly; 8/12/2008; 700+ words ; "Key molecules involved in notochord differentiation and function have...potential role for Mek1/2 during notochord development by using the small molecule...tail and an abnormal, undulated notochord. Using morphological analysis...
STUDY SHEDS LIGHT ON NERVE DEFECTS
News Wire article from: United Press International; 9/9/1998; 614 words ; ...questions about the classic model of the notochord, a vital rod-like structure that precedes...traditional understanding has been that the notochord signals neural cells to induce the formation...cord. But new data cast doubt on the notochord's role. In the latest report, in...
Research conducted at M. Anjomshoa and co-authors has provided new information about stem cell research.
Newspaper article from: Biotech Week; 4/22/2009; 700+ words ; ...coculture embryonic notochord model in vitro...bead-encapsulated notochords isolated from Hamburger...embryos. The use of notochord alone was not able...effectiveness of embryonic notochord coculture in providing...Cells with Chicken Notochords. Stem Cells and Development...
Evolutionary implications of FGF and distal-less expressions during proximal-distal axis formation in the ampulla of a direct-developing ascidian, Molgula pacifica. (fibroblast growth factor)
Magazine article from: The Biological Bulletin; 6/1/1998; ; 700+ words ; ...in ascidian development (11). When notochord progenitor cells were isolated from embryos...descendants of these cells expressed a notochord-specific protein, termed "Not-1...that FGF2 receptors may be present in notochord cells of indirect-developing embryos...
Research conducted at University of California has provided new information about life sciences.
Newspaper article from: Science Letter; 2/10/2009; 700+ words ; ...simple chordate Ciona intestinalis, the notochord plate consists of just 40 cells, which...in the developing nerve cord directs notochord intercalation through non-MAPK signaling...polarized actin-rich protrusions in notochord cells, resulting in defective notochord...
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