isoniazid

Home > ... > Medicine > Drugs > Pharmacology > ...

Essential reading Compare
side-by-side A Dictionary of Nursing The Columbia Encyclopedia, Sixth Edition

isoniazid

isoniazid , drug used to treat tuberculosis . Also known as isonicotinic acid hydrazide, isoniazid is the most effective antituberculosis drug currently available. The drug inhibits or kills the tubercle bacilli that cause the disease. It is usually given together with some other antituberculosis drug such as streptomycin or aminosalicylic acid to prevent emergence of drug resistant organisms (see drug resistance ). To prevent development of tuberculosis in individuals who have a positive reaction to a tuberculin skin test, isoniazid is given alone. Side effects are seen only with very high doses.

Create a link to this page

Copy and paste this link tag into your Web page or blog:

<a href="http://www.encyclopedia.com/topic/.aspx#1E1-isoniazi" title="Facts and information about isoniazid">isoniazid</a>

Give this article a thumbs-up on StumbleUpon

Cite this article
Pick a style below, and copy the text for your bibliography.

MLA
Chicago
APA

"isoniazid." The Columbia Encyclopedia, Sixth Edition. 2008. Encyclopedia.com. 2 Dec. 2009 <http://www.encyclopedia.com>.

"isoniazid." The Columbia Encyclopedia, Sixth Edition. 2008. Encyclopedia.com. (December 2, 2009). http://www.encyclopedia.com/doc/1E1-isoniazi.html

"isoniazid." The Columbia Encyclopedia, Sixth Edition. 2008. Retrieved December 02, 2009 from Encyclopedia.com: http://www.encyclopedia.com/doc/1E1-isoniazi.html

Learn more about citation styles

isoniazid

A Dictionary of Nursing | 2008 | Â© A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

isoniazid (isonicotinic acid hydrazide, INH) (I-soh-ny-ă-zid) n. a drug used in the treatment of tuberculosis, usually taken by mouth. Because tuberculosis bacteria soon become resistant to isoniazid, it is given in conjunction with other antibiotics.

Create a link to this page

Copy and paste this link tag into your Web page or blog:

<a href="http://www.encyclopedia.com/topic/.aspx#1O62-isoniazid" title="Facts and information about isoniazid">isoniazid</a>

Cite this article
Pick a style below, and copy the text for your bibliography.

MLA
Chicago
APA

"isoniazid." A Dictionary of Nursing. Oxford University Press. 2008. Encyclopedia.com. 2 Dec. 2009 <http://www.encyclopedia.com>.

"isoniazid." A Dictionary of Nursing. Oxford University Press. 2008. Encyclopedia.com. (December 2, 2009). http://www.encyclopedia.com/doc/1O62-isoniazid.html

"isoniazid." A Dictionary of Nursing. Oxford University Press. 2008. Retrieved December 02, 2009 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O62-isoniazid.html

Learn more about citation styles

Related entries from encyclopedias, dictionaries and thesauruses

A Dictionary of Nursing entry for INH

Rate these entries|See all related entries

Free newspaper and magazine articles

	Isoniazid preventive therapy and risk for resistant tuberculosis. Magazine article from: Emerging Infectious Diseases; 5/1/2006
	Failure of isoniazid chemoprophylaxis during infliximab therapy.(LETTERS)(Letter to the editor) Magazine article from: Emerging Infectious Diseases; 9/1/2007
	Pure red blood cell aplasia and isoniazid use.(LETTERS)(Clinical report) Magazine article from: Emerging Infectious Diseases; 9/1/2007

Facts and information from other sites

Related articles from newspapers, magazines, and more

	Isoniazid preventive therapy and risk for resistant tuberculosis. Magazine article from: Emerging Infectious Diseases; 5/1/2006; ; 700+ words ; ...context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly...concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its...effect of primary IPT on the risk for isoniazid-resistant TB. Different definitions...
	Isoniazid toxicity: A treatable cause of status epilepticus Magazine article from: Journal of Pediatric Neurology; 7/1/2009; ; 700+ words ; ...history of accidental ingestion of 13 tablets isoniazid-rifampicin (89 mg/kg isoniazid), 1 hr earlier, presented with generalized...phenobarbitone. Given in gram per gram amounts of the isoniazid ingested, intravenous pyridoxine (vitamin...
	Isoniazid- and ethambutol-induced psychosis.(Case Report)(Case study) Magazine article from: Annals of Thoracic Medicine; 10/1/2008; ; 700+ words ; ...associated psychoses were caused by isoniazid (INH), with ethambutol (EMB)-induced...and had no further psychotic symptoms. Isoniazid (INH) is included in all drug regimens...with an initial 2 months of rifampicin, isoniazid, ethambutol, and pyrazinamide followed...
	Failure of isoniazid chemoprophylaxis during infliximab therapy.(LETTERS)(Letter to the editor) Magazine article from: Emerging Infectious Diseases; 9/1/2007; ; 700+ words ; ...testing with purified protein derivative, isoniazid chemoprophylaxis was started 2 weeks...developed in the patient, caused by isoniazid-resistant Mycobacterium kansasii...the first documented case of failure of isoniazid prophylaxis due to the emergence of isoniazid...
	Epiroprim Plus Isoniazid Shows Strong Anti-M. tuberculosis Activity In Vitro. Newspaper article from: Drug Week; 4/20/2001; 700+ words ; ...its own but may be a useful adjunctive therapy to isoniazid - even in isoniazid-resistant strains. In vitro studies show that...M. tuberculosis, including those resistant to isoniazid and rifampin, and those susceptible to one or...
	Isoniazid drug and food interactions: How to manage or avoid. Magazine article from: The Journal of Critical Illness; 7/1/1999; ; 700+ words ; ...of Tennessee Health Science Center. Isoniazid (INH) remains a standard component...Mechanism of the inhibitory action of isoniazid on microsomal drug metabolism. Biochem...Hein DW. Clinical pharmacokinetics of isoniazid. C/in Pharmacokin. 1979;4:401...
	Detection of mutation in isoniazid-resistant Mycobacterium tuberculosis isolates from tuberculosis patients in Belarus.(Brief Communication) Magazine article from: Indian Journal of Medical Microbiology; 4/1/2008; ; 700+ words ; ...from patients in Belarus. Forty two isoniazid-resistant isolates were identified...Standard PCR method for detection of isoniazid resistance associated mutations was performed...population.[sup] [6] Resistance to isoniazid is increasing in Belarus because 88...
	Pure red blood cell aplasia and isoniazid use.(LETTERS)(Clinical report) Magazine article from: Emerging Infectious Diseases; 9/1/2007; ; 700+ words ; To the Editor: Isoniazid is a first-line drug in the treatment...include prevention as well as cure. Isoniazid is usually well tolerated, although...implicated (2), and few reports involving isoniazid have been published. We report a case...
	Seizures, Metabolic Acidosis and Coma Resulting from Acute Isoniazid Intoxication Magazine article from: Anaesthesia and Intensive Care; 8/1/2005; ; 700+ words ; SUMMARY Isoniazid is an anti-tuberculosis drug, used...and prophylaxis of tuberculosis. Acute isoniazid intoxication is characterized by a clinical...in a dose equivalent to the amount of isoniazid ingested, is the only effective antidote...
	Isoniazid safe for liver transplant candidates. Newspaper article from: TB & Outbreaks Week; 12/17/2002; 620 words ; ...writer - The potent antituberculosis agent isoniazid can be safely administered to patients...say. "Optimal timing of initiation of isoniazid chemoprophylaxis in liver transplant...Affairs Medical Center in Pittsburgh. Isoniazid therapy could be initiated during the...